PDGF Under-Eye Injections: A Regenerative Approach to Eye Rejuvenation

If you’ve been looking for a non-surgical way to refresh tired eyes, Platelet-Derived Growth Factor (PDGF) injections may be a treatment worth learning about. This innovative approach uses the body’s own regenerative capabilities to improve skin texture, reduce fine lines and crepiness, and restore a more youthful under-eye appearance.

What is PDGF and How Does It Work?

PDGF is a naturally occurring protein found in your blood platelets. It plays a key role in wound healing and tissue regeneration by stimulating cell growth, collagen production, and the formation of new blood vessels.

In aesthetic medicine, PDGF can be delivered directly into the delicate under-eye area to encourage your body to naturally repair and rejuvenate the skin. Over time, this can improve crepiness, mild hollowing, and fine lines—without adding bulk or creating an “overfilled” look.

Regenerative Medicine Meets Aesthetics

Regenerative medicine focuses on harnessing the body’s own healing factors to restore and repair tissues. Unlike fillers that physically add volume, PDGF works by triggering your skin to create its own improvements—making results appear gradual, natural, and long-lasting.

Treatment Process and Sessions Needed

Most patients benefit from a series of 2–4 sessions, spaced about 6-8 weeks apart. Because results build over time as your collagen remodels, you’ll typically see the most noticeable improvement 2–3 months after your last session.

Maintenance treatments may be recommended every 8-12 months to sustain your results.

Safety and Downtime

The risk of allergic reaction is extremely low. Side effects are generally mild and may include:

• Slight redness

• Mild swelling

• Tenderness at the injection site

• Bruising

  
  

These typically resolve within 1–3 days. Most people can return to work and normal activities the same day, though planning your session when you don’t have major events in the next 48 hours is ideal.

Who Should Avoid PDGF Under-Eye Treatments?

While safe for most healthy adults, PDGF injections are not recommended if you:

• Are pregnant or breastfeeding

• Have active skin infections in the treatment area

• Are undergoing chemotherapy or have uncontrolled systemic illness

A thorough consultation ensures this treatment is right for you.

The Bottom Line

PDGF under-eye injections offer a gentle, regenerative option for patients seeking subtle, natural improvement without dermal fillers. By stimulating your own collagen and tissue repair, results can be long-lasting and harmonious with your natural features.

If you’re curious about whether PDGF is the right choice for your eyes, schedule a consultation to discuss your goals, medical history, and a personalized treatment plan!