Restylane Refyne and Defyne are the newest addition to Galderma’s arsenal of anti-aging treatments. They are billed as the next generation of hyaluronic acid fillers in the fight against laugh lines. Restylane Refyne was approved to treat moderate wrinkles and folds from the nose to mouth, while Restylane Defyne is meant to plump and fill deep-set lines without the typical swelling seen in other products.
While there are other fillers on the market that can plump wrinkles, Refyne and Defyne are meant to give a more natural-looking result than previously thought possible. Galderma claims results can last up to 12 months. The new technology is called XpresHAn (also referred to as Optimal Balance Technology), which is pronounced like a French person trying to say the word expression—and it allows the hyaluronic acid gel to flex within the skin as you move your face. Kind of like jeans versus yoga pants for your face. So whether you’re smiling, frowning, or wrinkling your face any which way, the result looks soft and natural, not puffy or stiff. And again, the swelling is much much less than any traditional fillers on the market.